BOSTON (NBC News) --
Boston and its suburbs, universities and transit system were on total lockdown Friday as police hunted door to door for marathon bombing suspect Dzhokhar Tsarnaev -- on the loose after his accomplice brother was killed in a stunning chain of events that left one cop dead and another injured, officials said.
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During a desperate effort to flee after their photos were released by the FBI, the brothers carjacked a Mercedes SUV and told the driver they were the men behind Monday's double-blast attack at the race and had just killed a campus security officer, a source told NBC News. The driver was released unhurt.
The older brother, Tamerlan Tsarnaev, was killed after a wild chase and firefight, but Dzhokhar was still at large in a densely populated area, and an associate was being sought. Adding to the nightmare, an explosive was found in Boston Friday morning and disabled, an official said.
The suspects' uncle, Ruslan Tsarni, called them "losers" and urged Dzhokhar to turn himself in.
"We're ashamed," he thundered outside his Maryland home.